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Saturday, 23 September 2017
What is metabolic engineering? PDF Print

Metabolic engineering is a particular type of biochemical or bioprocess engineering. By definition, metabolic engineering deals with biological systems where DNA recombinant techniques are supposed to be applied. Therefore, the term metabolic engineering should only be employed where genetic (or genômica) engineering is part of the analysis. Metabolic engineering is then used to improve certain biological characteristics, such as cellular property, production of secondary metabolites, or a more resistant organism. The most widely used tool of the metabolic engineer is the Metabolic Flux Analysis (MFA). From the stoichiometric matrix one is able to estimate cellular fluxes (reaction rates) of several otherwise unknown metabolic routes.

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